1. What is AST/ALT Ratio?

Definition: The AST/ALT ratio is a comparison between two liver enzymes - aspartate aminotransferase (AST) and alanine aminotransferase (ALT).

Purpose: This ratio helps clinicians assess liver health and differentiate between various liver diseases.

2. How Does the Calculator Work?

The calculator uses the formula:

Where:

• \( Ratio \) — AST/ALT ratio (dimensionless)
• \( AST \) — Aspartate aminotransferase level (U/L)
• \( ALT \) — Alanine aminotransferase level (U/L)

Explanation: The AST value is divided by the ALT value to calculate the ratio, which provides insight into potential liver conditions.

3. Clinical Significance of AST/ALT Ratio

Details:

• Ratio < 1: Typically seen in acute viral hepatitis or non-alcoholic fatty liver disease
• Ratio > 1: May indicate alcoholic liver disease, cirrhosis, or other chronic liver conditions
• Ratio > 2: Strongly suggests alcoholic liver disease

4. Using the Calculator

Tips: Enter the AST and ALT values in U/L (units per liter) from blood test results. Both values must be > 0.

5. Frequently Asked Questions (FAQ)

Q1: What are normal AST and ALT levels?
A: Typically, AST: 10-40 U/L, ALT: 7-56 U/L, but ranges vary by lab and gender.

Q2: Why is the AST/ALT ratio important?
A: It helps differentiate between different types of liver damage and assess disease progression.

Q3: Can medications affect AST and ALT levels?
A: Yes, many medications can elevate liver enzymes. Always review medications with your doctor.

Q4: What if my ratio is exactly 1?
A: A ratio of 1 is generally considered normal, but should be interpreted with other test results and clinical context.

Q5: Should I be concerned about a high ratio?
A: Elevated ratios should be discussed with a healthcare provider for proper interpretation and potential further testing.