Suppression Ratio Formula:
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Definition: This calculator determines the suppression ratio (SR) which measures the proportion of suppressed events (Es) out of total events (Et) in breast cancer research.
Purpose: It helps researchers and clinicians quantify treatment effectiveness by measuring how many cancer-related events were suppressed.
The calculator uses the formula:
Where:
Explanation: The ratio represents the fraction of events that were successfully suppressed by the treatment or intervention.
Details: The SR is crucial for evaluating treatment efficacy, comparing different therapies, and assessing patient response to interventions.
Tips: Enter the number of suppressed events (must be ≤ total events) and total events (must be > 0). The calculator will compute the ratio.
Q1: What constitutes a "suppressed event" in breast cancer?
A: Typically refers to cancer cells or tumor growth that have been successfully inhibited by treatment.
Q2: What's considered a good suppression ratio?
A: Higher ratios indicate better suppression, with 1 being complete suppression and 0 indicating no effect.
Q3: Can the ratio be greater than 1?
A: No, since suppressed events cannot exceed total events. The calculator validates this.
Q4: How is this different from response rate?
A: Suppression ratio specifically measures inhibition of events, while response rate may include other measures.
Q5: What time period does this measure cover?
A: The time frame depends on the study design - could be weeks, months, or years of treatment.