1. What is a Testosterone/SHBG Ratio Calculator?

Definition: This calculator determines the ratio of testosterone to sex hormone-binding globulin (SHBG), which helps assess bioavailable testosterone levels.

Purpose: It helps healthcare professionals and individuals evaluate androgen status, especially in cases of suspected hormonal imbalances.

2. How Does the Calculator Work?

The calculator uses the formula:

Where:

• \( R \) — Testosterone/SHBG ratio (dimensionless)
• \( T \) — Testosterone level (nmol/L)
• \( SHBG \) — Sex hormone-binding globulin level (nmol/L)

Explanation: The ratio indicates what proportion of testosterone is potentially bioavailable, as SHBG binds testosterone and reduces its biological activity.

3. Importance of Testosterone/SHBG Ratio

Details: This ratio is clinically significant because:

• Helps assess androgen status more accurately than total testosterone alone
• Useful in evaluating conditions like hypogonadism, PCOS, and metabolic syndrome
• Correlates with symptoms of testosterone deficiency or excess

4. Using the Calculator

Tips: Enter testosterone level (nmol/L), SHBG level (nmol/L), and age. All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: What is a normal testosterone/SHBG ratio?
A: Normal ranges vary by age and lab, but generally 0.5-1.0 for adult males and 0.1-0.4 for adult females are typical.

Q2: Why include age in the calculation?
A: While age doesn't affect the ratio directly, reference ranges vary significantly by age, and results should be interpreted accordingly.

Q3: What does a high ratio indicate?
A: May suggest hyperandrogenism (in women) or adequate androgen activity (in men). Clinical context is essential.

Q4: What does a low ratio indicate?
A: May suggest reduced bioavailable testosterone, seen in hypogonadism, obesity, or conditions with elevated SHBG.

Q5: How often should this ratio be checked?
A: Frequency depends on clinical indication - typically when evaluating symptoms or monitoring treatment for hormonal conditions.